Fig. 7.

Triple immunofluorescent labeling for the astroglial marker GFAP (green), the nuclear marker Hoechst 33342 (blue), and AT1R, AT2R or PRR (red) in monkey and human substantia nigra compacta. Labeling for AT1R appeared mostly located at the cell surface (arrows in a–h), and AT2R and PRR labeling at the cytoplasm and nuclear levels (arrowheads in i–x). AT1R angiotensin II type 1 receptor, AT2R angiotensin II type 2 receptor, GFAP glial fibrillary acidic protein, PRR prorenin/renin receptor. Scale bar 20 µm