. Author manuscript; available in PMC: 2013 Apr 13.

Published in final edited form as: Caries Res. 2012 Apr 13;46(3):177–184. doi: 10.1159/000337282

Table 4.

Single SNP Association Analyses with Dental Caries Scores^*

Caries Scores	Association Model	# of informative families	DSPP rs2615487	AQP5 rs1996315	KLK4 rs2235091
D2fs-total	Risk	49	C(0.17)	G(0.41)	G(0.18)
	Protective	147	T(0.0002/0.0009)	A(0.02/0.08)	A(0.008/0.02)
D2fs-pit/fissure	Risk	41	C(0.24)	G(0.21)	G(0.38)
	Protective	154	T(0.0004/0.002)	A(0.05/0.07)	A(0.004/0.03)
D2fs-smooth surface	Risk	28	C(0.33)	G(0.89)	G(0.02/0.13)
	Protective	166	T(0.002/0.004)	A(0.008/0.02)	A(0.02/0.08)

: Entries in the table are the associated SNP alleles and their corresponding nominal P values and empirical P values by permutation test (in format of nominal P/empirical P); Empirical P values are reported only for those significant observations (nominal P≤0.05, highlighted in bold).