Figure 3.
Effects of cromolyn on IgE-dependent PMC degranulation (a – f) or PGD2 synthesis (g – i) in vitro. IgE-sensitized PMCs from female rats (a, d and g) or mice (b, c, e, f, h and i) were stimulated with DNP-HSA with or without cromolyn (added simultaneously). N = 3 – 10 per group from 1 – 2 independent experiments. ## p < 0.01, # p < 0.05, †† p < 0.01, † p < 0.05; N.S.: not significantly different versus corresponding values (vehicle or 100 μM cromolyn) for groups not treated with stimuli. ** p < 0.01, * p < 0.05; n.s.: p > 0.05.