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Incidence of colonic tumors and prolapsed rectum/bleeding anus in C57BL/6 versus Nrf2 knockout (KO) mice after azoxymethane (AOM)/DSS treatment (20 wks). The incidence of colonic tumors per mouse and prolapsed rectum/bleeding anus was significantly higher in Nrf2 knockout mice compared with WT C57BL/6 mice. Fisher’s exact test was used to compare the difference between groups.
*, P < 0.01.
