Figure 2. Dicer is required for the formation and function of WAT in vivo.
(A) H&E stain of the epidermis from 12-day old Dicer-wildtype mice and Dicer-mutant mice. Scale bar represents 1000μm. (B) H&E stain of abdominal WAT of Dicer-wildtypemice and Dicer-mutant mice. Figures shown at 10X (top) and 40X (bottom) magnifications. Scale bars represent 100μm and 10μm, respectively. (C) Quantitative PCR results of adipogenic-related transcripts present in WAT of 10-day old Dicer-wildtype mice and Dicer-mutant mice. The average value for each wildtype transcript was set at 1. Bars represent SD values obtained from eight sibling pairs wherein each pair consists of one mutant and one wildtype mouse.