Figure 5. Effects of LXA4 on the expressions of MMP-2, -9 by corneal fibroblasts.

Cells were cultured in the absence or presence of IL-1β (0.1ng/mL) and the indicated concentrations of LXA4. Culture supernatants were then subjected to gelatin zymography. The positions of bands corresponding to pro-MMP-2 and pro-MMP-9 and active MMP-2, -9 are indicated on the right, and those of molecular size are shown on the left. Data are representative of three times.