Table 3.
Results of SEM of longitudinal effect of COMT on global cognition at ages 8 and 15 years.
| Boys |
Girls |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | Age 8 |
Age 15 |
n | Age 8 |
Age 15 |
|||||
| β | p | β | p | β | p | β | p | |||
| rs737865 | 1134 | −0.047 | 0.341 | −0.095 | 0.046 | 1157 | −0.028 | 0.568 | 0.002 | 0.971 |
| rs165599 | 1146 | 0.018 | 0.718 | 0.012 | 0.802 | 1156 | −0.037 | 0.449 | −0.06 | 0.22 |
| Diplotype* | 1156 | −0.01 | 0.792 | −0.033 | 0.362 | 1163 | −0.016 | 0.662 | −0.029 | 0.415 |
Note: Diplotype = rs6269–rs4818–rs4680; reference groups are CC–for rs737865, GG–for 165599, ValA/ValA–for Nackley's diplotype. β based on standardised outcomes and unstandardized predictor.