Table 3.
Demographic, cognitive and neuroimaging data in the high and low 18F-florbetaben retention groups
| All MCI (n = 45) | ||
|---|---|---|
| Low Aβ (SUVR < 1.45) | High Aβ (SUVR ≥ 1.45) | |
| Number (% of total) | 21 (47) | 24 (53) |
| Age | 71.8 ± 6.1 | 73.5 ± 6.9 |
| Years of education | 13.5 ± 3.0 | 13.8 ± 4.2 |
| MMSE | 27.9 ± 1.4 | 26.7 ± 1.9* |
| CDR | 0.4 ± 0.2 | 0.5 ± 0.0* |
| CDR SOB | 1.3 ± 0.9 | 1.6 ± 1.0 |
| Composite EM | -1.4 ± 0.8 | -2.8 ± 1.0* |
| Composite NM | -1.0 ± 0.9 | -0.8 ± 0.8 |
| Neocortical SUVR | 1.30 ± 0.09 | 1.75 ± 0.19* |
| Hippocampal volume (cm3) | 7.4 ± 1.1 | 6.9 ± 0.8 |
| WMH volume (cm3) | 9.9 ± 10.2 | 10.5 ± 11.8 |
Aβ, β-amyloid; CDR, Clinical Dementia Rating; EM, episodic memory z score; MCI, mild cognitive impairment; NM, nonmemory z score; SOB, sum of boxes, SUVR, standard uptake value ratio; WMH, white matter hyperintensities. *P < 0.05.