Table 4.
Common autoimmune manifestations in common variable immunodeficiency
| Mount Sinai 1999 [3](n = 248) | Mount Sinai 2011 [38](n = 473) | DEFI 2010 [62](n = 311) | |
|---|---|---|---|
| AIHA | 4.8% (12/248) | 7% (33/473) | 5.4% (17/311) |
| ITP | 6% (15/248) | 14.2% (67/473) | 13.2% (41/311) |
| Neutropenia | <1% (2/248) | <1% (<5/473) | 3.2% (10/311) |
| Rheumatoid arthritis | 3.6% (9/248) | 3.2% (15/473) | 2.6% (8/311) |
| Vitiligo | NS | <1% (<5/473) | 3.9% (12/311) |
| Sicca syndrome, Sjögren's syndrome | <1% (2/248) | <1% (<5/473) | 4.2% (13/311) |
| Autoimmune thyroiditis, diabetes mellitus, | <1% (2/248) | <1% (<5/473 | 3.9% (12/311) |
| multiple sclerosis | |||
| Alopecia | 1.6% (4/248) | 1.1% (5/473) | NS |
| Pernicious anemia | 1.2% (3/248) | <1% (<5/473) | NS |
| Systemic lupus erythematosus | <1% (2/248) | <1% (<5/473) | <1% (1/311) |
AIHA, autoimmune hemolytic anemia; ITP, immune thrombocytopenic purpura; NS, not specified.