Table 1.
Patients' characteristics
| Baseline cytokine secretion | Stimulation | |||||||
|---|---|---|---|---|---|---|---|---|
| Normal control | Granulomatosis with polyangiitis | Normal control | Granulomatosis with polyangiitis | |||||
| (n = 19) | (n = 20) | (n = 10) | (n = 10) | |||||
| Age (yrs, mean and range) | 39.50 (18 to 76) | 51.55 (24 to 71) | 43.30 (23 to 56) | 50.80 (24 to 71) | ||||
| Sex | 11 male, 8 female | 12 male, 8 female | 7 male, 3 female | 7 male, 3 female | ||||
| First GPA manifestation till study entry (yrs, median and range) | 3.8 (19 to 0) | 3.3 (9 to 0) | ||||||
| First GPA diagnosis till study entry (yrs, median and range) | 1.6 (19 to 0) | 3.1 (9 to 0) | ||||||
| Serologic parameters | ||||||||
| mean value | SD | mean value | SD | mean value | SD | mean value | SD | |
| WBC (cells/nl) | 6.74 | 1.55 | 8.22 | 2.82 | 7.87 | 1.97 | 7.77 | 2.33 |
| ESR 1st h (mm) | 8.14 | 3.94 | 33.00 | 27.60 | 8.00 | 2.92 | 52.40 | 35.61 |
| median | range | median | range | median | range | median | range | |
| CRP (mg/dl) | 1.30 | 0.9 to 5.8 | 0.70 | 0 to 8.6 | 1.50 | 1.3 to 3.4 | 0.85 | 0.1 to 8.6 |
| C-ANCA-titre (1:) | 80 | 0 to 2560 | 640 | 0 to 2560 | ||||
| P-ANCA-titre (1:) | 0 | 0 to 640 | 0 | 0 to 61 | ||||