Table 2.
Relation of CRP genotypes to baseline CRP levels
| SNP | HWE (p) | Genotype | Geometric mean CRP (mg/L) (SD) | n | P value |
|---|---|---|---|---|---|
| rs1205 | 0.60 | GG | 32.17 (2.75) | 272 | Ref. |
| GA | 31.51 (2.67) | 270 | 0.81 | ||
| AA | 26.39 (2.70) | 57 | 0.17 | ||
| rs1800947† | 0.23 | CC | 31.93 (2.70) | 533 | Ref. |
| CG | 26.47 (2.76) | 66 | 0.15 | ||
| rs3091244_T | 0.33‡ | XX | 29.09 (2.73) | 278 | Ref. |
| XT | 34.40 (2.72) | 261 | 0.05 | ||
| TT | 28.94 (2.53) | 60 | 0.97 | ||
| rs3091244_A¶ | XX | 31.36 (2.70) | 550 | Ref. | |
| XA | 30.32 (2.68) | 33 | 0.85 |
SNP, single-nucleotide polymorphism; HWE, Hardy-Weinberg Expectation; SD, standard copies of T allele. For the A allele of rs3091244: XX, no copies of A allele; XA one copy of A allele; AA two copies of A allele.
† No homozygote minor allele observed in this dataset.
‡ rs3091244_T & rs3091244_A SNPs combined to give HWE of rs3091244.
¶ Homozygote minor alleles grouped with heterozygotes.