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. 2012 Oct 18;14(5):R226. doi: 10.1186/ar4065

Figure 4.

Figure 4

Effects of glucocorticoids or TNFα on Wnt-related gene expression. (A and B) Effect of glucocorticoid treatment (100 nM dexamethasone) or TNFα (10 ng/ml) on expression of Wnt-related genes (n = 96) was examined using a targeted microarray. Genes with the greatest fold change are shown (the effect of TNFα on DKK1 and FRZB expression was not significant). A full list of the genes included in the array and their full gene titles is given in Additional file 1, Table S1. (C) Real-time PCR validation of changes in mRNA expression for FRZB and WNT2 in response to dexamethasone (DEX) or TNFα. *P < 0.05, **P < 0.01 relative to control. Results shown are the combined results of three separate FLS lines.