Table 2.
Case | Material sampling | Organ involvement | ||
---|---|---|---|---|
PBMC | CD3/CD20 | LSGa | ||
1 | ○ | ○ | MD, lymph node, lung | |
2 | ○ | ○ | MD, lymph node | |
3 | ○ | ○ | MD | |
4 | ○ | MD, lymph node | ||
5 | ○ | MD, lung | ||
6 | ○ | ○ | MD, lymph node, para-aorta swelling | |
7 | ○ | ○ | Intraorbital mass, retroperitoneal fibrosis | |
8 | ○ | MD | ||
9 | ○ | MD | ||
10 | ○ | MD | ||
11 | ○ | MD | ||
12 | ○ | MD | ||
13 | ○ | MD | ||
14 | ○ | MD, lung | ||
15 | ○ | MD, liver |
PBMCs, peripheral blood mononuclear cells; CD3/CD20, CD3-positive T cells and CD20-positive B cells sorted from PBMCs; LSG, labial salivary gland; MD, Mikulicz disease (salivary and lacrimal glands). aAll LSG samples satisfied histopathologic findings of the comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD) 2011.