Table 2.
Measurement 1 | Measurement 2 | Measurement 3 | |
---|---|---|---|
(Before hemodilution) | (After hemodilution) | (After protein infusion) | |
RCV (ml) | 1,273 ± 249¶ | 947 ± 195§ | 947 ± 195* |
PV (ml) | 2,686 ± 297║ | 2,554 ± 378║ | 2,987 ± 408‡ |
BV (ml) | 3,959 ± 387¶ | 3,501 ± 499‡ | 3,934 ± 500¶ |
HKWB | 0.32 ± 0.05‡ | 0.27 ± 0.04‡ | 0.24 ± 0.04‡ |
HKLV | 0.35 ± 0.04‡ | 0.28 ± 0.04‡ | 0.25 ± 0.04‡ |
Fcell | 0.91 ± 0.03‡ | 0.97 ± 0.02§ | 0.97 ± 0.02§ |
ESL (ml) | 339 ± 130‡ | 99 ± 54§ | 120 ± 77§ |
Cumulative urine production# (ml) | 635 ± 200† | 884 ± 171† | |
Increase in interstitial water content# (ml) | 2,157 ± 606† | 1,719 ± 680† |
*Not reassessed, but taken from measurement 2 (no further blood withdrawal), #since the beginning of hemodilution procedure (for calculations see Materials and Methods section), §P < 0.05 vs. measurement 1, ¶P < 0.05 vs. measurement 2, ║P < 0.05 vs. measurement 3, ‡P < 0.05 vs. both other measurements, †P < 0.05 vs. basal and other measurement, respectively. For further details on the statistical analysis see Appendix 1. Values are mean ± standard deviation (SD). BV, blood volume; ESL, volume of the endothelial surface layer; ; HKLV, large vessel hematocrit; HKWB, whole body hematocrit; PV, plasma volume; RCV, red cell volume.