Table 1.
Characteristics by AKI level among 30,762 ICU patients, Northern Denmark, 2005 to 2010
| Without AKI n = 25,969 (84.4%) |
AKI-risk n = 1,986 (6.5%) |
AKI-injury n = 1,311 (4.3%) |
AKI-failure n = 1,496 (4.9%) |
|
|---|---|---|---|---|
| Age | ||||
| Median age (IQR) | 64 (49, 75) | 72 (61, 80) | 71 (59, 80) | 69 (59, 78) |
| Gender | ||||
| Female | 11,172 (43.0%) | 878 (44.2%) | 645 (49.2%) | 657 (43.9%) |
| Male | 14,797 (57.0%) | 1,108 (55.8%) | 666 (50.8%) | 839 (56.1%) |
| Charlson comorbidity index scorea | ||||
| Low (score 0) | 13,862 (53.4%) | 798 (40.2%) | 510 (38.9%) | 556 (37.2%) |
| Medium (score 1 to 2) | 8,654 (33.3%) | 804 (40.5%) | 507 (38.7%) | 579 (38.7%) |
| High (score ≥ 3) | 3,453 (13.3%) | 384 (19.3%) | 294 (22.4%) | 361 (24.1%) |
| Chronic kidney diseaseb | ||||
| Yes | 3,283 (12.6%) | 395 (19.9%) | 199 (15.2%) | 470 (31.4%) |
| No | 22,686 (87.4%) | 1,591 (80.1%) | 1,112 (84.8%) | 1,026 (68.6%) |
| Surgical statusc, d | ||||
| Non-surgical | 9,495 (36.6%) | 892 (44.9%) | 593 (45.2%) | 786 (52.5%) |
| Surgical | ||||
| Acute non-cardiac | 8,271 (31.8%) | 752 (37.9%) | 564 (43.0%) | 554 (37.0%) |
| Acute cardiac | 920 (3.5%) | 102(5.1%) | 40 (3.1%) | 34 (2.3%) |
| Elective non-cardiac | 3,939 (15.2%) | 188 (9.5%) | 101 (7.7%) | 106 (7.1%) |
| Elective cardiac | 3,344 (12.9%) | 52 (2.6%) | 13 (1.0%) | 16 (1.1%) |
| Primary diagnosis during current hospitalization | ||||
| Septicemia | 232 (0.9%) | 100 (5.0%) | 127 (9.7%) | 187 (12.5%) |
| Other infectious diseases | 2,329 (9.0%) | 254 (12.8%) | 182 (13.9%) | 194 (13.0%) |
| Endocrinology diseases | 359 (1.4%) | 65 (3.3%) | 52 (4.0%) | 82 (5.5%) |
| Cardiovascular diseases | 7.377 (28.4%) | 464 (23.4%) | 196 (15.0%) | 183 (12.2%) |
| Respiratory diseases | 1,427 (5.5%) | 180 (9.1%) | 77 (5.9%) | 66 (4.4%) |
| Gastrointestinal or liver diseases | 2,416 (9.3%) | 322 (16.2%) | 266 (20.3%) | 239 (16.0%) |
| Cancer or other neoplasm | 3.410 (13.1%) | 175 (8.8%) | 139 (10.6%) | 130 (8.7%) |
| Trauma or poisoning | 4,651 (17.9%) | 168 (8.5%) | 110 (8.4%) | 96 (6.4%) |
| Other | 3,758 (14.5%) | 258 (13.0%) | 162 (12.4%) | 319 (21.3%) |
| Laboratory information | ||||
| Baseline creatinine measured | 17,384 (66.9%) | 1,530 (77.0%) | 950 (72.5%) | 1.164 (77.8%) |
| ICU admission creatinine, μmol/L (IQR) | 75 (61, 92) | 137 (112, 168) | 190 (153, 230) | 375 (280, 516) |
| ICU treatments | ||||
| Acute renal replacement therapy | 482 (1.9%) | 206 (10.4%) | 220 (16.8%) | 561 (37.5%) |
| Mechanical ventilation | 9,673 (37.2%) | 965 (48.6%) | 697 (53.2%) | 719 (48.1%) |
| Inotropes/vasopressors | 7,823 (30.1%) | 939 (47.3%) | 756 (57.7%) | 864 (57.8%) |
| Length of admission | ||||
| In-hospital days, median (IQR) | 10 (4, 19) | 13 (5, 26) | 14 (5, 30) | 16 (6, 33) |
| In-hospital days before ICU admission, median (IQR) | 1 (0, 2) | 1 (0, 3) | 1 (0, 3) | 1 (0, 3) |
Results are presented as number (percent) of patients unless stated otherwise.
aCharlson comorbidity index score after exclusion of kidney diseases.
beGFR < 60 ml/min per 1.73 m2.
cSurgical status and cardiac surgical status identified by surgery and type of surgery on or up to 7 days before ICU admission.
dAcute and elective status classified according to hospital admission type.
AKI, acute kidney injury; CI, confidence interval; ICU, intensive care unit; IQR, interquartile range.