Table 2.
Surgical procedures and performance
| Total cohort | Control - no bicarbonate | Intervention - bicarbonate | Significance, P-value | |
|---|---|---|---|---|
| Number | 584 | 304 (52.1%) | 280 (47.9%) | |
| Type of procedure | ||||
| CABG | 222 (38.1) | 110 (36.3%) | 112 (40.0%) | 0.160 |
| Valve surgery +/- varia | 176 (30.1%) | 93 (30.7%) | 82 (28.9%) | |
| CABG +/- valve +/- varia | 120 (20.6%) | 71 (23.4%) | 49 (17.5%) | |
| Aortic surgery +/- valve +/- varia | 54 (9.3%) | 21 (6.9%) | 33 (11.8%) | |
| Various procedures | 10 (1.7%) | 8 (2.6%) | 3 (1.1%) | |
| Aortic surgery +/- CABG | 2 (0.3%) | 1 (0.3%) | 1 (0.4%) | |
| Duration of surgery, minutes | 254 (247, 261) | 249 (242, 260) | 258 (250, 268) | 0.406 |
| Duration of CPB, minutes | 115 (110, 119) | 115 9 (107, 122) | 115 (109, 120) | 0.756 |
| Crossclamp time, minutes | 89.5 (84, 93) | 88.5 (82, 93) | 90 (83, 96) | 0.539 |
| ECLS | 7 (1.2%) | 3 (1.0%) | 4 (1.4%) | 0.913 |
| IABP | ||||
| No IABP | 556 (95.2%) | 289 (95.1%) | 267 (95.4%) | 0.445 |
| IABP before CPB | 6 (1.0%) | 2 (0.7%) | 4 (1.4%) | |
| IABP during CPB | 8 (1.4%) | 6 (2.0%) | 2 (0.7%) | |
| IABP after CPB | 8 (1.4%) | 3 (1.0%) | 5 (1.8%) | |
| IABP on ICU | 6 (1.0%) | 4 (1.3%) | 2 (0.7%) | |
| Circulatory arrest | 21 (3.6%) | 13 (4.3%) | 8 (2.9%) | 0.485 |
| Lowest body temperature, °C | 32 (32, 32) | 32 (32, 32) | 32 (32, 32) | 0.615 |
Surgical procedures and surgical core data are shown for patients undergoing elective on-pump cardiac surgery with or without a perioperative infusion of bicarbonate. CABG: coronary artery bypass grafting; CPB: cardiopulmonary bypass; ECLS: extracorporeal life support; IABP: intra-aortic balloon pump. Data are given as absolute numbers (percentage) for nominal variables and as median (95% confidence interval).