Table 1.
Description of the study population by period and ICU, Edouard Herriot Hospital, Lyon (France), 2004-2010.
| Characteristics | Intervention group: Interrupted surveillance, unit A |
Control group: Continuous surveillance, unit B |
||||
|---|---|---|---|---|---|---|
| Period 1 2004 to 2006 (n = 448) | Period 2 2007 to 2010 (n = 492) | P | Period 1 2004 to 2006 (n = 743) | Period 2 2007 to 2010 (n = 881) | P | |
| Categorical variable, n (%) |
||||||
| Gender, male | 308 (68.8) | 320 (65.0) | 0.23 | 439 (59.1) | 531 (60.3) | 0.63 |
| Patient origin | 0.004 | <0.001 | ||||
| Home | 70 (15.6) | 114 (23.2) | 421 (56.7) | 421 (47.8) | ||
| Other unit/hospital | 378 (84.4) | 378 (76.8) | 322 (43.3) | 460 (52.2) | ||
| Immunosuppresseda | 153 (34) | 263 (53) | <0.001 | 98 (13.2) | 175 (19.9) | <0.001 |
| Diagnosis categorya | <0.001 | 0.060 | ||||
| Medical | 265 (59.2) | 161 (32.7) | 660 (88.8) | 807 (91.6) | ||
| Surgery | 183 (40.9) | 331 (67.3) | 83 (11.2) | 74 (8.4) | ||
| Antibioticsa | 284 (63.4) | 230 (46.8) | <0.001 | 397 (53.4) | 629 (71.4) | <0.001 |
| Deceased in-hospital | 60 (13.5) | 91 (18.8) | 0.028 | 236 (31.9) | 256 (29.1) | 0.22 |
| Continuous variable, mean (SD) |
||||||
| Age, yearsa | 56.3 (14.9) | 58.5 (15.5) | 0.022 | 61.1 (16.4) | 60.7 (59.6) | 0.61 |
| SAPSIIa | 51.7 (17.9) | 45.4 (21.0) | <0.001 | 55.6 (19.8) | 55.5 (18.8) | 0.95 |
| Length of hospital stay, days | 12.2 (18.6) | 15.3 (25.7) | 0.038 | 14.8 (20.3) | 12.0 (17.0) | 0.0023 |
| Length of invasive mechanical ventilation, days | 7.7 (14.5) | 11.3 (24.7) | 0.007 | 11.1 (19.0) | 8.5 (14.5) | 0.0015 |
| Incidence of VAP | ||||||
| Number of VAP | 35 | 84 | 68 | 99 | ||
| Attack rateb | 7.8 | 17.1 | <0.001 | 9.2 | 11.2 | 0.17 |
| Incidencec (95% CI) | 13.4 (9.5-18.4) |
22.9 (18.4-28.2) |
11.2 (8.7-14.1) |
17.1 (14.0-20.8) |
||
NOTE: CI, confidence interval; SD, standard deviation; SAPSII, simplified acute physiological score II; VAP, ventilator-associated pneumonia. a At ICU admission. b Number of VAP per 100 intubated patients. c Number of VAP per 1,000 intubation-days.