Systemic FG-7142 administration and intra-ACC infusion of SR95531 impair 3-CSRT performance. Rats were administered vehicle or 5 mg/kg of i.p. FG-7142 (a–d; n=15 and 14, respectively) or SR95531 at doses of 0, 1, or 3 ng per side (ACC microinjection e–h; n=8, 5, and 3, respectively). Performance was measured in terms of percent accuracy (a, e), percent omissions (b, f), premature responses (c, g), and total responses (d, h). Data are presented as mean±SEM. Asterisks indicate significant differences from vehicle (*p<0.05; **p<0.01)