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Epigenomic profiling. Specific combinations of chromatin marks denote different classes of functional elements, including poised enhancers, active enhancers, transcribed loci, and promoters. For example, promoters are enriched for H3K4me3, H3K27ac, and H3K79me2; active enhancers are depleted for H3K4me3 and enriched for H3K27ac.
