Box 1.

General Criteria for MCI (Modified after [3])

●  Diagnosis based on clinical judgement

●  Report of cognitive decline by the patient and / or an informant

Cognitive impairment in one or more domains (e.g. memory, attention, language, visuospatial skills, perceptual speed or executive functioning).: memory impairment (amnestic MCI) multidomain MCI (either amnestic or non-amnestic) single non-memory domain MCI

●  Evidence of decline present in neuropsychological assessment.

●  Mainly preserved basic activities of daily living (i.e. no dementia)