Table 5.
Budget impact model results (base case and sensitivity analyses) (Can$)
| Base case | Baseline | Year 1 | Year 2 | Year 3 | Total 3 years |
|---|---|---|---|---|---|
| % Switching (IVIG to SCIG) | — | 50 | 50 | 50 | — |
| Number of patients IVIG | 456 | 228 | 228 | 228 | — |
| Number of patients SCIG | 0 | 228 | 228 | 228 | — |
| Total cost IVIG ($) | 1 172 525 | 586 262 | 586 262 | 586 262 | 1 758 787 |
| Total cost SCIG ($) | 0 | 198 178 | 126 358 | 126 358 | 450 893 |
| Incremental cost ($) | — | −388 085 | −459 905 | −459 905 | −1 307 894 |
| % Increment | — | −33 | −39 | −39 | −37 |
| Sensitivity analysis A (IVIG 13 visits—4 h) | |||||
| Total cost IVIG ($) | 1 065 931 | 532 966 | 532 966 | 532 966 | 1 598 897 |
| Total cost SCIG ($) | 0 | 198 178 | 126 358 | 126 358 | 450 893 |
| Incremental cost ($) | — | −334 788 | −406 608 | −406 608 | −1 148 004 |
| % Increment | — | −31 | −38 | −38 | −36 |
| Sensitivity analysis B (IVIG 17 visits—6 h) | |||||
| Total cost IVIG ($) | 1 936 550 | 968 275 | 968 275 | 968 275 | 2 904 826 |
| Total cost SCIG ($) | 0 | 198 178 | 126 358 | 126 358 | 450 893 |
| Incremental cost ($) | — | −770 098 | −841 918 | −841 918 | −2 453 933 |
| % Increment | — | −40 | −43 | −43 | −42 |
| Sensitivity analysis C (switching 75%) | |||||
| Number of patients IVIG | 456 | 114 | 114 | 114 | — |
| Number of patients SCIG | 0 | 342 | 342 | 342 | — |
| Total cost IVIG ($) | 1 172 525 | 293 131 | 293 131 | 293 131 | 879 393 |
| Total cost SCIG ($) | 0 | 297 266 | 189 536 | 189 536 | 676 339 |
| Incremental cost (4) | — | −582 127 | −689 857 | −689 857 | −1 961 841 |
| % Increment | — | −50 | −59 | −59 | −56 |
IVIG, intravenous immunoglobulin; SCIG, subcutaneous immunoglobulin.