TABLE 1.
Initial-adherence tertile comparisons
Skipped doses in months 1–6: (initial tertiles) |
||||
---|---|---|---|---|
A <1.5% (n=45) | B 1.5%–5% (n=45) | C ≥5% (n=47) | P | |
Missed doses (%) | ||||
Months 1–6 | 0 (0–1.3) a | 2.4 (1.6–5) b | 12 (4–84) c | <0.001 |
Months 19–24 | 0.6 (0–42) a | 2.8 (0–53) b | 10 (0–99) c | <0.001 |
Months 43–48 | *0.9 (0–27) a | *3.9 (0–41) b | 16(0–97)c | <0.001 |
No. holidays ≥2 d | ||||
Months 1–6 | 0(0–2)a | 1 (0-4)b | 4(0-37)c | <0.001 |
Months 19–24 | 1 (0–25)A | *2 (0–25) b | 4(0–33)b | <0.001 |
Months 43–48 | *1(0–5)a | *2 (0–28) b | 8(0–42)b | <0.001 |
Maximum holiday (d) | ||||
Months 1–6 | 0(0-3)a | 2(0–5)b | 4(0–34)c | <0.001 |
Months 19–24 | *2 (0–10) a | 2(0–32)b | 4(0–175)c | <0.001 |
Months 43–48 | 2(0-41)a | *2 (0–7) b | 3(0–119)b | 0.008 |
Values are medians (minimum–maximum). Sample sizes are given in Figure 2.
Between-group comparisons are within rows, with the overall P value given in the table. Significant differences between groups are indicated by lower case letters (a, b, or c): those with different letters are significantly different (P<0.05), whereas those sharing the same letter are not.
Significant within-group changes from the first 6 mo are indicated with an asterisk (*).