. Author manuscript; available in PMC: 2013 Feb 25.

Published in final edited form as: Transplantation. 2009 Mar 15;87(5):711–718. doi: 10.1097/TP.0b013e318195c3d5

TABLE 3.

Outcomes by initial-adherence tertiles of 137 patients with adequate monitor data

	Skipped dosses in months 1–6: (initial tertile)
Late outcomes^a	A <1.5% (n=45)	B 1.5%–5% (n=45)	C >5% (n=47)	Overall P
Rejection
Late acute rejection	8	9	15	0.224
Late acute rejection rate	2.2 (±.7) ^a	2.5 (±.8) ^a	6.4 (±1.3) ^b	0.025
Late acute rejection rate (≤5 yr)	1.9 (±1) ^a	3.9 (±1.4) ^a	10.8 (±2) ^b	0.001
Late acute rejection rate (>5 yr)	2.4 (±1)	1.3 (±.7)	1.6 (±1)	0.436
Graft loss
Late graft loss before death	9	9	14	0.438
Late graft loss before death rate	2.2 (±0.7)	2.1 (±0.7)	3.7 (±1)	0.357
Late graft loss before death rate (≤5 yr)	1.9 (±1) a	2.0 (±1) a	5.7 (±2) b	0.036
Late graft loss before death rate (>5 yr)	2.4 (±1)	2.1 (±1)	1.6 (±1)	0.811
Any event
No event before death	32	28	28	0.484
No event including death	24	23	20	0.549

Between-group comparisons are within rows, with the overall P value given in the table. Significant differences between groups are indicated by lower case letters (a, b, or c): those with different letters are significantly different (P<0.05), whereas those sharing a letter are not significantly different.

Late events occurred 90 d or more after discharge from hospital at transplantation, and are reported and compared in two ways: number of affected patients; event rate (± standard error) per 100 patient-years during all followup before and after the 5th year post-transplant.