Table 1. Distribution of the Val62Ile genotype for cases and controls and the allele frequencies.

Authors	Case (N)	genotype		Control (N)	genotype		aHWE
		GG/GA/AA	A/G		GG/GA/AA	A/G	P value
bHageman et al. [19]	228	190/34/4	42/414	68	44/18/6	30/106	0.0577
cHageman et al. [19]	546	395/135/16	167/925	261	148/90/23	136/386	0.0896
Chen et al. [20]	163	95/55/13	81/245	244	96/110/38	186/302	0.4883
Fuse et al. [21]	80	40/31/9	49/111	192	86/84/22	128/256	0.8286
Mori et al. [22]	188	102/71/15	101/275	139	42/73/24	121/157	0.4209
Kim et al. [23]	114	60/42/12	66/162	187	55/87/45	177/197	0.3606
Lee et al. [24]	72	41/27/4	35/109	93	36/41/16	73/113	0.4664
Xing et al. [25]	350	9/100/241	582/118	2365	154/868/1343	3554/1176	0.3901
Bergeron et al. [26]	421	324/84/13	110/732	215	123/77/15	107/323	0.5382
Goto et al. [27]	191	94/89/8	105/277	188	60/92/36	164/212	0.9447
Hayashi et al. [28]	947	538/341/68	477/1417	1338	456/649/233	1115/1561	0.9365
Hecker et al. [29]	122	91/31/0	31/213	147	85/51/11	73/221	0.392
Liu et al. [30]	222	100/92/30	152/292	235	78/119/38	195/275	0.5099
Yang et al. [31]	109	56/40/13	66/152	150	51/69/30	129/171	0.4505
Tanaka et al. [32]	685	386/263/36	335/1035	277	100/141/36	213/341	0.2091

^aHWE=Hardy–Weinberg Equilibrium; ^bHageman=2005a in Iowa cohort; ^cHageman=2005b in Columbia cohort.