Table 3. MMP-1 and MMP-7 SNP genotype frequencies in POAG and PACG patients and unaffected controls.
|
|
Controls n=236 (%) |
POAG n=224 (%) |
p (χ2) |
OR (95% CI) |
PACG
n=164 (%) |
p (χ2) |
OR (95% CI) |
|---|---|---|---|---|---|---|---|
| MMP-1= c.-1607-1606insGG | |||||||
|
1G |
151(64.0) |
103(46) |
<0.001 (14.22) | 2.04 (1.38-3.01) | 86(52.4) |
0.02 (4.57) | 1.61 (1.05-2.47) |
| 2G | 85(36.0) | 121(54.0) | 78(47.6) | ||||
| MMP-7 = c.-181T>C | |||||||
|---|---|---|---|---|---|---|---|
|
T |
143(60.6) |
136(60.7) |
0.97 (0.00) | 0.99 (0.67-1.47) | 91(55.5) |
0.30 (1.04) | 1.23 (0.81-1.89) |
| C | 93(39.4) | 88(39.3) | 73(44.5) | ||||