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. Author manuscript; available in PMC: 2013 Feb 25.
Published in final edited form as: Pharm Res. 2008 Jan 31;25(3):483–488. doi: 10.1007/s11095-007-9523-x

Table I.

Ability to Correctly Classify BCS Permeability for Estimated CLogP and Log P vs Metabolism as Compared to Human Jejunal Permeability Measures Using Metoprolol as the Reference

CLogP Log P Extensive vs. Poor Metabolisma
19 of 29 19 of 27 27 of 29
65.5% 70.4% 93.1%
a

Using 70% as the cutoff