Table 1.
Demographic and Clinical Characteristics of Patients at First Combination Antiretroviral Therapy Initiation, Among Persons Who Subsequently Initiated a Second Regimen and Met the Study Inclusion Criteria
| Characteristic | N (%) or median (IQR) |
|---|---|
| Total | 488 |
| Age, years | 37 (31–44) |
| Sex | |
| Male | 333 (68.2%) |
| Female | 155 (31.8%) |
| Race/ethnicity | |
| Black/African-American | 325 (66.6%) |
| White | 124 (25.4%) |
| Hispanic | 19 (3.9%) |
| Other | 20 (4.1%) |
| HIV risk group | |
| MSM | 140 (28.7%) |
| IDU | 118 (24.2%) |
| Heterosexual | 200 (41.0%) |
| Other/Unknown | 30 (6.1%) |
| Prior ADI | 165 (33.8%) |
| CD4 cell count, cells/mm3 | 135 (27–302) |
| HIV-1 RNA level, copies/ml | 83,875 (22,218–284,817) |
| cART anchor agent | |
| NNRTI | 237 (48.6%) |
| PI (unboosted) | 160 (33.8%) |
| PI/r | 91 (18.7%) |
IQR, interquartile range; MSM, men who have sex with men; IDU, intravenous drug use; ADI, AIDS-defining clinical condition; cART, combination antiretroviral therapy; NNRTI, nonnucleoside reverse transcriptase inhibitor; PI, protease inhibitor; PI/r, ritonavir-boosted protease inhibitor.