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Incidence and disease induction in uMT- or AID- deficient mice.
| Genotype | Dose (ug) | Incidence | Day of onset (Ave ± SEM)* | Peak MSOD (Ave ± SEM)* |
|---|---|---|---|---|
| uMT+/+ | 100 | 100 (8/8) | 11.1 ± 1.1 | 3.4 ± 0.2 |
| uMT − / − | 100 | 25 (2/8) | 20** | 3** |
| AID+/+ | 100 | 100 (9/9) | 11.3 ± 0.6 | 3.7 ± 0.2 |
| AID − / − | 100 | 10 (1/10) | 16.5** | 4** |
*Calculated only for those animals that received a disease score greater than or equal to 1.
**SEM not shown as number of animals in calculation is less than 3.
