. Author manuscript; available in PMC: 2013 Feb 25.

Published in final edited form as: J Pharm Sci. 2011 May 26;100(9):3831–3842. doi: 10.1002/jps.22640

Table 3.

Eprosartan AUC 0→60_min for time-course studies and/fold increase for significant changes vs. normal serum in rat hepatocytes.

Eprosartan 10μM	Normal Serum	Hemodialysis Serum	Rifampin 10μM
AUC of Cumulative Drug (μM^* min)	575 ± 32	615 ± 60	572 ± 37
AUC of Intracellular Drug (μM^* min)	59.7 ± 18.2	^*114 ± 23/1.91	74.7 ± 27.2

Results shown as average ± SD, /ratio compared to normal serum,

p<0.05 by ANOVA, n=4