Table 3.
Odds ratios for ADHP problems in groups of offspring differing in paternal zygosity, paternal alcohol dependence, and cotwin alcohol dependence (AD)^
| ADHP-4B | ADHP-6B | ADHP-4N | ADHP-6N | |||||
|---|---|---|---|---|---|---|---|---|
| Risk status | Prev (%) |
OR (95% CI) |
Prev (%) |
OR (95% CI) |
Prev (%) |
OR (95% CI) |
Prev (%) |
OR (95% CI) |
| 1. Dad AD | 19.6 | 1.52* (1.02–2.28) |
8.7 | 1.38 (0.78–2.44) |
8.1 | 1.33 (0.75–2.36) |
6.9 | 1.26 (0.68–2.32) |
| 2. Dad UN – MZ Cotwin AD | 21.6 | 1.72* (1.03–2.88) |
12.3 | 2.03* (1.03–4.01) |
9.9 | 1.64 (0.83–3.26) |
8.0 | 1.47 (0.70–3.10) |
| 3. Dad UN – DZ cotwin AD | 14.5 | 1.06 (0.59–1.89) |
5.0 | 0.77 (0.32–1.86) |
3.5 | 0.54 (0.20–1.45) |
3.5 | 0.60 (0.22–1.66) |
| 4. UN/UN | 13.8 | 1.00 | 6.4 | 1.00 | 6.3 | 1.00 | 5.6 | 1.00 |
^
Child gender (male) was a significant covariate (p<.01) for all ADHP categories.
*
p<.05