Table 4.
Multivariate associations between ADHP measures, family risk status, prenatal exposure variables, and parental psychopathology^.
| ADHP-4B | ADHP-6B | ADHP-4N | ADHP-6N | |||||
|---|---|---|---|---|---|---|---|---|
| Risk status | Prev (%) |
OR (95% CI) |
Prev (%) |
OR (95% CI) |
Prev (%) |
OR (95% CI) |
Prev (%) |
OR (95% CI) |
| 1. Dad AD | 19.6 | 1.10 (0.70–1.72) |
8.7 | 0.88 (0.46–1.70) |
8.1 | 0.78 (0.41–1.50) |
6.9 | 0.67 (0.33–1.34) |
| 2. Dad UN – MZ Cotwin AD | 21.6 | 1.42 (0.81–2.51) |
12.3 | 1.57 (0.74–3.34) |
9.9 | 1.25 (0.57–2.72) |
8.0 | 1.04 (0.44–2.43) |
| 3. Dad UN – DZ cotwin AD | 14.5 | 0.88 (0.48–1.61) |
5.0 | 0.58 (0.23–1.47) |
3.5 | 0.40 (0.14–1.13) |
3.5 | 0.43 (0.15–1.24) |
| 4. UN/UN | 13.8 | 1.00 | 6.4 | 1.00 | 6.3 | 1.00 | 5.6 | 1.00 |
| Prenatal risk | ||||||||
| Smoked during pregnancy | 25.4 | 1.69** (1.19–2.40) |
10.7 | 1.32 (0.78–2.23) |
11.4 | 1.72* (1.03–2.88) |
8.7 | 1.30 (0.74–2.31) |
| Drank before knew pregnant | 20.6 | 0.84 (0.55–1.26) |
10.5 | 0.74 (0.40–1.34) |
9.6 | 0.67 (0.36–1.24) |
8.9 | 0.71 (0.36–1.36) |
| Drank after knew pregnant | 25.2 | 1.64* (1.07–2.51) |
15.7 | 3.16** (1.67–5.99) |
14.8 | 3.39** (1.80–6.37) |
14.2 | 3.74** (1.90–7.34) |
| Parental psychopathology | ||||||||
| Paternal DSM-III-R nicotine dependence | 20.2 | 1.19 (0.86–1.68) |
9.5 | 1.30 (0.77–2.19) |
9.0 | 1.39 (0.81–2.39) |
8.1 | 1.59 (0.87–2.91) |
| Maternal DSM-IV alcohol dependence | 29.1 | 1.62 (0.95–2.76) |
14.3 | 1.56 (0.73–3.34) |
14.6 | 1.71 (0.85–3.43) |
13.6 | 1.92 (0.90–4.10) |
| Maternal DSM-IV ADHD | 43.0 | 4.31** (2.57–7.23) |
26.4 | 5.71** (2.98–10.93) |
20.3 | 4.27** (2.21–8.23) |
17.7 | 4.21** (2.08–8.49) |
^
AD=alcohol dependence. Multivariate model covariates included based on Hosmer & Lemeshow39 criteria.
Adjusted multivariate model covariates (not in table): Child gender (male) remained significant (p<.01) for all ADHP categories. Divorce was non-significant for ADHP-4B (p=.25), ADHP-6B (p=.23), or ADHP-4N (p=.09) in the multivariate model; however it remained significant for the multivariate model of ADHP-6B (p=.04).
*
p<.05
**
p<.01