Table 1.
Median staining intensity (score) of renal Hsp90α, Hsp90β, and pc-Src protein expressions.
| Median staining intensity (score) | ||||||
|---|---|---|---|---|---|---|
| Hsp90α | Hsp90β | pc-Src | ||||
| sham | Aldo | sham | Aldo | sham | Aldo | |
| Cortex | ||||||
| Glomerulus | 2 | 2 | 3 | 4 | 1 | 2 |
| PCT | 2 | 3 | 2 | 3 | 0 | 3 |
| DCT | 1 | 1 | 1 | 2 | 1 | 0 |
| CCD | 3 | 2 | 1 | 3 | 2 | 1 |
| Pcap | 1 | 2 | 3 | 1 | 0 | 0 |
|
| ||||||
| Outer medulla | ||||||
| Outer stripe | ||||||
| TALH | 3 | 3 | 4 | 4 | 2 | 1 |
| MCD | 2 | 2 | 4 | 4 | 2 | 1 |
| PTs | 2 | 1 | 2 | 3 | 0 | 0 |
| Inner stripe | ||||||
| TALH | 3 | 4 | 3 | 3 | 1 | 0 |
| MCD | 3 | 3 | 3 | 3 | 1 | 0 |
| VR | 2 | 3 | 4 | 3 | 3 | 4 |
| tLH | 1 | 2 | 2 | 2 | 1 | 4 |
|
| ||||||
| Inner medulla | ||||||
| MCD | 4 | 3 | 4 | 3 | 2 | 1 |
| VR | 2 | 3 | 2 | 2 | 4 | 4 |
| tLH | 2 | 2 | 2 | 3 | 2 | 2 |
Staining intensity: 0: negative, no reactivity; 1: trace, faint, or pale brown staining with less membrane reactivity; 2: weak, light brown staining with incomplete membrane reactivity; 3: moderate, shaded of brown staining of intermediate darkness with usually almost complete membrane reactivity; 4: strong, dark brown to black staining with usually complete membrane pattern, producing a thick outline of the cell [5].
PCT: proximal convoluted tubule; DCT: distal convoluted tubule; CCD: cortical collecting duct; Pcap: peritubular capillary; TALH: thick ascending limb of Henle's loop; MCD: medullary collecting duct; PTs: proximal straight tubule; VR: vasa recta; tLH: thin limb of Henle's loop.