Table 3.
The odds ratio (OR) for increasing inflammatory mark by genetic variations of GSTs in relation to blood lead level >6.47 μg/dL.
| GST genetic variation | CRP* | |
|---|---|---|
| OR | 95% CI | |
| GSTP1 (Ile105Val) | ||
| Ile/Ile | 1 | Reference |
| Ile/Val and Val/Val | 1.46 | 1.05−2.20 |
| GSTM1 | ||
| +/+ | 1 | Reference |
| −/− | 1.32 | 1.03−1.69 |
| GSTT1 | ||
| +/+ | 1 | Reference |
| −/− | 1.65 | 1.17−2.35 |
| GSTM1 and GSTT1 | ||
| +/+ | 1 | Reference |
| +/− or −/+ | 1.07 | 0.88−1.31 |
| −/− | 1.98 | 1.47−2.55 |
CRP: C-reactive protein; OR: odds ratio; CI: confidence interval.
*With adjustment for age, body mass index, smoking status, alcohol use, and blood pressure.