Figure 6.

The pathology of liver in recipient rats with liver transplantation (HE, original magnification ×400). The recombination vector of lentivirus contains shRNA targeting the 4-1BB gene was constructed. The liver transplantation was performed using the two-cuff technique. BN recipient rats were infected by the recombinant LVs. The pathology of liver in recipient rats was observed by H-E staining 7 days after liver transplantation. Model: liver transplantation model group; LV-NC: negative-control shRNA group; LV-sh4-1BB1: pcDNA-CMV-sh4-1BB1-Lentivector group.