The effect of each type of SPION on S. aureus over the course of 24 hours with optical density measurements taken every 4 minutes. A) Raw data and B) select time periods of 3, 10, and 24 hours. Results of this experiment showed that the best SPION for treating S. aureus biofilm growth was SPION functionalized with carboxylate as well as iscoyanate. Data represent mean ± SEM, n = 3 with *P < 0.1 indicating statistical significance compared to S. aureus alone and **P < 0.1 indicating statistical significance compared to controls.
Notes: Results of this experiment showed that the best SPION for treating S. aureus biofilm growth was SPION functionalized with carboxylate as well as iscoyanate. Data represent mean ± SEM, n = 3 with *P < 0.1 indicating statistical significance compared to S. aureus alone and **P < 0.1 indicating statistical significance compared to controls (unfunctionalized).
Abbreviation: Unfunctionalized OD, optical density; SEM, Standard error of the mean.