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Summary of enzymatic potency for compound 4 against other proteases
| Enzyme | IC50a |
|---|---|
| Caspase I | >10 |
| Cathepsin B | >30 |
| Cathepsin G | >10 |
| Chymotrypsin | >25 |
| Elastase, leukocyte | >30 |
| MMP-1 | >10 |
| Trypsin | >10 |
a All values are in μm. Value given is the highest concentration tested, which in all cases gave <50% inhibition.
