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Co-localization studies of ECE-2 and ECE-1b with APP. SH-SY5Y-APP cells transiently transfected with either ECE-2 or ECE-1b were stained with the corresponding ECE antibody along with a C-terminal APP antibody. Both ECE-2 and ECE-1b showed partial co-localization with compartments rich in APP and/or CTFs.
