Table 3. IL1B-31, IL1RN and TNFA-307 genotypic frequencies in H. pylori-positive (n = 47) and –negative children (n = 78).
All childrenn (%) | H. pylori-positiven (%) | H. pylori-negativen (%) | |
IL1B-31a | |||
T/T | 37 (29.8) | 16 (34.8) | 21 (26.9) |
T/C | 63 (50.8) | 20 (43.5) | 42 (55.2) |
C/C | 24 (19.4) | 10 (21.7) | 14 (17.9) |
IL1RN VNTRb | |||
1/1 | 82 (66.2) | 30 (65.2) | 52 (66.7) |
1/2 | 35 (28.2) | 15 (32.6) | 20 (25.6) |
2/2 | 07 (5.6) | 01 (2.2) | 06 (7.7) |
TNFA-307 | |||
G/G | 87 (69.6) | 32 (68.1) | 55 (70.5) |
G/A | 38 (30.4) | 15 (31.9) | 23 (29.5) |
It was not possible to genotype 1 H. pylori-positive children for IL1B-31 and 1 for IL1RN.
1 indicates all the long alleles and 2 the short allele. The loci did not deviate significantly from the expected Hardy-Weinberg distribution (P = 0.90 for IL1B-31, P = 0.26 for IL1RN and P = 0.08 for TNFA-307) and all segregated independently.