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. 2013 Feb 25;8(2):e57805. doi: 10.1371/journal.pone.0057805

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© 2013 Zhang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Human sequences are shown when available. (A) AR, adrenergic receptor; AT1R, angiotensin II type 1 receptor; MTR, melatonin receptor; EDG4, lysophosphatidic acid receptor; HRH1, histamine H1 receptor; CCR, C–C chemokine receptor; BKRB2, B2 bradykinin receptor; RL3R1, relaxin-3 receptor; C3AR, C3a anaphylatoxin chemotactic receptor; CML1, chemokine receptor-like 1 receptor; CLTR, cysteinyl leukotriene receptor; MCHR, melanin-concentrating hormone receptor; P2RY, purinergic receptor; GHSR, growth hormone secretagogue receptor; GASR, gastrin/cholecystokinin receptor; AA3R, adenosine A3 receptor; MTLR, motilin receptor; EDNR, endothelin receptor; RL3R, relaxin-3 receptor; FFAR, free fatty acid receptor; 5HT, serotonin receptor; DRD, dopamine receptor; TAAR, trace amine-associated receptor. The first residue Tyr in the alignment represents the end of the 7^th transmembrane domain characterized by the NPxxY motif.