Skip to main content
. 2013 Feb 25;8(2):e56447. doi: 10.1371/journal.pone.0056447

Figure 3. ACA suppressed T cells but not B cells in mice with OVA-induced asthma.

Figure 3

(a) ACA dose-dependently suppressed the upregulation of CD8+ cytotoxic T cells in the lungs. (b) ACA suppressed the upregulation of CD4+ Th cells as effectively as dexamethasone. (c) ACA did not affect CD79α+ B cells in the lungs of mice with OVA-induced asthma. Immunopositive cells were counted in five randomly selected nonoverlapping fields (×200 magnification) of three separately immunostained lung sections per animal. A, vehicle control; B, OVA-induced asthma model; C, dexamethasone; D, 25 mg/kg/day ACA; E 50 mg/kg/day ACA.