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. 2013 Feb 25;8(2):e56447. doi: 10.1371/journal.pone.0056447

Table 1. ACA reduced eosinophil numbers in bronchoalveolar lavage fluid recovered from mice with OVA-induced asthma.

NEUs LYMs EOSs BASs LUCs
(×106) (×106) (×106) (×106) (×106)
Vehicle control 0.03±0.009 0.03±0.011 0.01±0.012 0.01±0.004 0.05±0.040
Albumin-induced asthma model 0.04±0.012 0.11±0.052 a 1.14±0.270 a 0.01±0.004 0.10±0.023
Dexamethasone treatment 0.02±0.005 0.03±0.010 b 0.27±0.150 b 0.01±0.002 0.08±0.034
25 mg/kg/day ACA treatment 0.07±0.077 0.08±0.049 0.73±0.299 a,b,c 0.01±0.023 0.13±0.059 a
50 mg/kg/day ACA treatment 0.02±0.007 0.04±0.019 b 0.34±0.198 b,d 0.01±0.004 0.07±0.019

Results are expressed as mean ± SD (n = 7). NEU, neutrophils; LYMs, lymphocytes; EOSs, eosinophils; BASs, basophils; LUCs, large unstained cells.

a

p<0.01 vs. CON (vehicle control); b p<0.01 vs. OVA (OVA-induced asthma model); c p<0.01 vs. DEX (dexamethasone treatment); d p<0.01 vs. ACA-25 mg (25 mg/kg/day ACA treatment).