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. 2013 Feb 25;8(2):e57143. doi: 10.1371/journal.pone.0057143

Table 2. EDIPS cases identified by high-risk FINDRISC10 score or by cut-points for fasting plasma glucose (FPG) and glycated Haemoglobin (HbA1c) as specified by NICE, ADA and WHO with risk statistics for intervention and control groups compared.

Moderate or lower risk High or greater risk
FNDRISC a 10 <15 ≥15
EDIPS cases n (%) 387 (51·7)) 330 (44·1)
Hazard ratio (95% CI) P value and B(SE) for intervention/control incidence 0·62 (0·37 to 1·05) P = 0·072 −0.5(0.3) 0·30 (0·20 to 0·51) P<0·001 −1.2(0.3)
FPG (mmoll 1 ) Lower risk High risk Diabetic range
NICE ranges <5·5 5·5 to 6·9 (99 to 125 mg/dl) ≥7·0
EDIPS cases n (%) 178 (23·8) 500 (66·8) 71 (9·5)
Hazard ratio (95% CI) P value and B(SE) for intervention/control incidence 0·29 (0·12 to 0·71) P = 0·007 −1.2(0.5) 0·48 (0·30 to 0·75) P<0·001 −0.7(0.2)
ADA ranges <5·6 5·6 to 6·9 (100 to 125 mg/dl) ≥7·0
EDIPS cases n (%) 214 (28·6) 464 (61·9) 71 (9·5)
Hazard ratio (95% CI) P value and B(SE) for intervention/control incidence 0·26 (0·11 to 0·61) P = 0·002 −1.4(0.4) 0·51(0·32 to 0·82) P = 0·005 −0.7(0.2)
WHO ranges <6·1 6·1 to 6·9 (110 to 125 mg/dl) ≥7·0
EDIPS cases n (%) 404 (53·9) 268 (35·8) 71 (9·5)
Hazard ratio (95% CI) P value and B(SE) for intervention/control incidence 0·43 (0·24 to 0·77) P = 0·005 −0.8(0.3) 0·40 (0·22 to 0·71) P = 0·002 −1.0(0.3)
HbA1cb (%) Lower risk High risk Diabetic range
NICE and UK-NSC ranges <6·0 6·0 to 6·4 (42–47 mmol/mol) ≥6·5
EDIPS cases n (%) 539 (72·0) 134 (17·9) 59 (7·9)
Hazard ratio (95% CI) P value and B(SE) for intervention/control incidence 0·44 (0·27 to 0·68) P<0·001 −0.8(0.2) 0·34 (0·16 to 0·72) P = 0·005 −1.1(0.4)
ADA ranges <5·7 5·7 to 6·4 (39–47 mmol/mol) ≥6·5
EDIPS cases n (%) 357 (47·7) 316 (42·2) 59 (7·9)
Hazard ratio (95% CI) P value and B(SE) for intervention/control incidence 0·42 (0·26 to 0·70) P<0·001–0.8(0.3) 0·38 (0·19 to 0·76) P = 0·006 −1.0(0.4)