Table 3. EDIPS cases identified by FINDRISC10 and high risk cut-points for fasting plasma glucose (FPG) and glycated Haemoglobin (HbA1c) as specified by NICE, ADA and WHO with risk statistics for intervention and control groups compared.
| FINDRISC score cut-points | ||
| Moderate or greater risk (≥12) | High or greater risk (≥15) | |
| FINDRISC a score only | ||
| EDIPS cases n (%) | 519 (69·3) | 330 (44·1) |
| Hazard ratio (95% CI), P value and B(SE) for intervention/control incidence | 0·43 (0·28 to 0.66) | 0·30 (0·20 to 0·51) |
| P<0·001–0.8(0.2) | P<0·001 −1.2(0.3) | |
| FPG (mmoll −1 ) | ||
| NICE high risk range (5·5 to 6·9) | ||
| EDIPS cases n (%) | 354 (49·4) | 224 (31·2) |
| Hazard ratio (95% CI), P value and B(SE) for intervention/control incidence | 0·48 (0·28 to 0·83) | 0·39 (0·20 to 0·78) |
| P = 0·008 −0.9(0.4) | P = 0·008 −0.9(0.4) | |
| ADA high risk range (5·6 to 6·9) | ||
| EDIPS cases n (%) | 328 (45·7) | 209 (29·1) |
| Hazard ratio (95% CI), P value and B(SE) for intervention/control incidence | 0·51 (0.30 to 0.87) | 0·41 (0·21 to 0·83) |
| P = 0·014 −0.7(0.3) | P = 0·007 −0.9(0.4) | |
| WHO high risk range (6·1 to 6·9) | ||
| EDIPS cases n (%) | 198 (27·6) | 62 (8·9) |
| Hazard ratio (95% CI), P value and B(SE) for intervention/control incidence | 0·37 (0.23 to 0.64) | 0·31 (0·13 to 0·73) |
| P = 0·003 −1.0(0.3) | P = 0·007 −0.9(0.4) | |
| HbA1c b (%) | ||
| NICE and UK-NSC high risk range (6·0 to 6·4) | ||
| EDIPS cases n (%) | 96 (13·7) | 62 (8·9) |
| Hazard ratio (95% CI) P value and B(SE) for intervention/control incidence | 0·46 (0·19 to 1·10) | 0·35 (0·12 to 1·00) |
| P = 0·08 −0.8(0.4) | P = 0·05 −1.1(0.5) | |
| ADA high risk range | ||
| EDIPS cases n (%) | 227 (32·4) | 158 (22·6) |
| Hazard ratio (95% CI),P value and B(SE) for intervention/control incidence | 0·43 (0·24 to 0·76) | 0·28 (0·13 to 0·59) |
| P = 0·004 −0.8(0.3) | P = 0·001 (−1.2(0.4) | |
a
n = 717.
b
n = 732.