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. 2013 Feb 25;8(2):e57098. doi: 10.1371/journal.pone.0057098

Table 2. Effect of NU6027 and Cisplatin in Chinese hamster ovary and human ovarian cancer cells.

Cell lines NU6027 (µM;Ac) Cisplatin (µM;Bc) NU6027 (µM;Ae) Cisplatin (µM;Be) D
CHO EM-C11 4 1.5 8 3 1
EM-C12 4 1.5 10 2.5 1
OVCAR-3 siRNA_1 6 1 10 2.5 1
siRNA_2 6 1 12 2 1
SiRNA_3 6 1 10 3 0.93
OVCAR-4 siRNA_1 6 1 9 3 0.99
siRNA_2 6 1 10 2.5 1
SiRNA_3 6 1 10 2.5 1

Ac and Bc, concentrations of drugs used in the combination treatment; Ae and Be concentrations of NU6027 alone and cisplatin alone respectively that produce a similar magnitude of effect; D (combination index.).