Table III.

Evaluation of In Situ Nasal Gels of LOR

Formulation code	clarity	pH	Gelling temp (°C)	Gelling time (s)	Viscosity of sol (cps)	Drug content (%)	Gel strength (s)	Mucoadhesive-strength (dyne/cm2)
F1	Clear	5.75 ± 0.05	33.7 ± 0.47	12.6 ± 0.47	28.34 ± 0.47	77.41 ± 0.40	26.51 ± 0.67	3,626.12 ± 0.34
F2	Clear	5.63 ± 0.01	34.3 ± 0.47	14.6 ± 0.94	27.39 ± 1.25	96.42 ± 0.32	27.82 ± 1.26	3,920.05 ± 0.47
F3	Clear	5.70 ± 0.01	32.6 ± 0.47	10.6 ± 0.94	35.35 ± 0.94	75.21 ± 0.48	33.30 ± 0.94	6,157.67 ± 0.2 3
F4	Clear	5.59 ± 0.01	32.1 ± 0.47	11.3 ± 0.47	34.63 ± 1.24	98.91 ± 0.23	35.61 ± 1.41	6,161.38 ± 0.47
F5	Clear	5.76 ± 0.01	30.7 ± 0.47	8.3 ± 0.47	28.82 ± 0.47	80.32 ± 0.37	38.81 ± 0.87	4,540.61 ± 1.24
F6	Clear	5.64 ± 0.01	30.2 ± 0.23	9.7 ± 0.47	29.09 ± 0.81	92.81 ± 0.54	39.00 ± 0.81	4,847.33 ± 0.46
F7	Clear	5.81 ± 0.01	29.2 ± 0.82	5.7 ± 0.47	43.61 ± 0.47	82.20 ± 0.08	45.61 ± 1.2 7	7,137.64 ± 0.81
F8	Clear	5.34 ± 0.02	28.7 ± 0.47	6.7 ± 0.47	43.36 ± 0.94	97.72 ± 0.59	44.36 ± 0.94	7,676.09 ± 0.97