Table II.
Variation of L. paracasei L26 Viable Cells (Mean ± Standard Deviation) in Tablets after 45 Days of Storage at 23°C/33% of Relative Humidity and in MRS Solution Throughout the Simulated Gastrointestinal Conditions
| Gastrointestinal compartment | Sampling (min) | Tablets (CFU/g) | MRS solution (CFU/mL) |
|---|---|---|---|
| Initial | 0 | (6.26 ± 0.40) × 106 | NDa |
| Mouth (pH 6, 37°C, 200 rpm) | 90 | (3.24 ± 0.53) × 106 | NDa |
| Esophagus–stomach (ΔpH 6 to 2, 37°C, 130 rpm) | |||
| Duodenum (ΔpH 2 to 5, 37°C, 45 rpm) | 120 | (4.05 ± 0.88) × 106 | NDa |
| Ileum (ΔpH 5 to 6.5, 37°C, 45 rpm) | 240 | (7.72 ± 0.17) × 106 | (1.34 ± 0.30) × 105 |
aNo viable cells detected in first decimal dilution