Skip to main content
. 2012 Dec 12;14(1):121–127. doi: 10.1208/s12249-012-9898-9

Table II.

Variation of L. paracasei L26 Viable Cells (Mean ± Standard Deviation) in Tablets after 45 Days of Storage at 23°C/33% of Relative Humidity and in MRS Solution Throughout the Simulated Gastrointestinal Conditions

Gastrointestinal compartment Sampling (min) Tablets (CFU/g) MRS solution (CFU/mL)
Initial 0 (6.26 ± 0.40) × 106 NDa
Mouth (pH 6, 37°C, 200 rpm) 90 (3.24 ± 0.53) × 106 NDa
Esophagus–stomach (ΔpH 6 to 2, 37°C, 130 rpm)
Duodenum (ΔpH 2 to 5, 37°C, 45 rpm) 120 (4.05 ± 0.88) × 106 NDa
Ileum (ΔpH 5 to 6.5, 37°C, 45 rpm) 240 (7.72 ± 0.17) × 106 (1.34 ± 0.30) × 105

aNo viable cells detected in first decimal dilution