Table I.
Dissolution Endpoints (T end) Measured by DSC for STZ/PVP, SDM/PVP, SMZ/PVP and SDZ/PVP Systems
| X PVP | T end (°C) STZ/PVP | T end (°C) SDM/PVP | T end (°C) SMZ/PVP | T end (°C) SDZ/PVP |
|---|---|---|---|---|
| 0.0 | 202.5 ± 0.4 | 198.9 ± 0.1 | 237.5 ± 0.1 | 252.7 ± 0.1 |
| 0.1 | 199.9 ± 0.3 | 196.7 ± 0.0 | 232.7 ± 0.1 | 248.2 ± 0.2 |
| 0.2 | 195.4 ± 0.2 | 193.8 ± 0.0 | 230.6 ± 0.1 | 244.3 ± 0.0 |
| 0.3 | 186.4 ± 1.2 | 189.2 ± 0.2 | 228.2 ± 0.2 | 241.2 ± 0.2 |
| 0.4 | 173.2 ± 1.7 | 179.8 ± 1.5 | 224.3 ± 0.3 | 238.3 ± 0.0 |
| 0.5 | – | 165.1 ± 1.9 | 209.9 ± 4.0 | 233.6 ± 0.7 |
| 0.6 | – | 146.7 ± 2.8 | – | 217.9 ± 1.4 |
Each value is the average of two measurements. The value after ± is the standard deviation
X pvp weight fraction of PVP®