Table II.
Dissolution Endpoints (T end) Measured by DSC for STZ/Soluplus®, SDM/Soluplus®, SMZ/Soluplus® and SDZ/Soluplus® Systems
| X Soluplus® | T end (°C) STZ/Soluplus® | T end (°C) SDM/Soluplus® | T end (°C) SMZ/Soluplus® | T end (°C) SDZ/Soluplus® |
|---|---|---|---|---|
| 0.0 | 202.5 ± 0.4 | 198.9 ± 0.1 | 237.5 ± 0.1 | 252.7 ± 0.1 |
| 0.1 | 200.7 ± 0.1 | 197.8 ± 0.2 | 233.8 ± 0.1 | 247.2 ± 0.4 |
| 0.2 | 200.0 ± 0.1 | 196.2 ± 0.0 | 231.9 ± 0.1 | 244.0 ± 0.1 |
| 0.3 | 195.8 ± 0.0 | 193.6 ± 0.0 | 230.2 ± 0.1 | 242.0 ± 0.1 |
| 0.4 | 191.4 ± 0.1 | 189.7 ± 0.0 | 228.2 ± 0.1 | 240.0 ± 0.0 |
| 0.5 | 183.8 ± 0.0 | 183.7 ± 0.0 | 224.2 ± 0.0 | 237.7 ± 0.0 |
| 0.6 | 170.1 ± 0.0 | 173.8 ± 0.0 | 214.6 ± 0.2 | 234.1 ± 0.1 |
| 0.7 | – | 165.4 ± 0.4 | 201.8 ± 0.6 | 227.1 ± 0.0 |
X Soluplus® weight fraction of Soluplus®
Each value is the average of two measurements. The value after ± is the standard deviation