Table V.
Evaluation of Gels
Formulation batch no. | Clarity | pH | Gelation temperature (°C) | Mucoadhesive strength (dyn/cm2) | Gel strength | Drug content (%) |
---|---|---|---|---|---|---|
T2 | ++ | 4.8 | 31°C | 1,160 ± 5.207 | 44 | 98.24 ± 0.072 |
T5 | +++ | 5.2 | 33°C | 981 ± 4.333 | 48 | 97.65 ± 0.070 |
T14 | ++ | 5.5 | 30°C | 904 ± 6.96 | 45 | 97.79 ± 0.043 |
T17 | +++ | 5.7 | 30°C | 1,017 ± 5.548 | 46 | 98.01 ± 0.061 |
Values are expressed as mean ± SD; n = 3, p value < 0.0045. p < 0.05 considered statistically significant