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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Genes Brain Behav. 2012 Nov 27;12(2):241–249. doi: 10.1111/j.1601-183X.2012.00867.x

Figure 7.

Figure 7

Compromised spatial learning in GIR −/− mice in the Morris water maze (MWM) test. (a) Attenuation in the decline of latency to find the platform was observed in GIR −/− mice (overall genotype effect, F =9.08; p<0.05). Analysis of individual days showed a reduced decline in latency time to find platform in −/− mice (# Day 2: p=0.06; # Day 3: p=0.08 versus GIR +/+ mice). (b) The groups did not differ in probe trial testing 24 hr after the last training session. Data are mean ± SEM of 3 trials per day for time to reach the goal during 4 days of training (n=8–9 /group)